Corazón alimentado con pasto (bovino) (libre de EEB), hígado alimentado con pasto (bovino) (libre de EEB). Otros ingredientes: Cápsula de metilcelulosa.

Los adultos toman 3 cápsulas al día según las indicaciones de un profesional de la salud con 8 onzas de agua o su bebida favorita. Puede tomarse con o sin alimentos.

PRECAUCIÓN: No exceda la dosis recomendada. Las mujeres embarazadas, las madres lactantes, los niños menores de 18 años y las personas con una afección médica conocida deben consultar a un médico antes de usar este o cualquier suplemento dietético. Tenga cuidado si tiene alergias o sensibilidades a alguno de los ingredientes enumerados. Mantener fuera del alcance de los niños y las mascotas. No lo utilice si el sello de seguridad está dañado o falta. Guardar en un lugar fresco y seco. Utilice este producto únicamente como complemento alimenticio. No utilizar para reducir peso.

Beef Heart

M. Faber, F.A.M. Wenhold. 16 - Trace elements and oral health. Michael Wilson. In Woodhead Publishing Series in Food Science. Technology and Nutrition. Food Constituents and Oral Health. Woodhead Publishing. 2009. 331-349. 9781845694180. DOI: 10.1533/9781845696290.2.331

P.A. Tsuji, J.A. Canter, L.E. Rosso. Trace Minerals and Trace Elements. Benjamin Caballero, Paul M. Finglas, Fidel Toldrá. Encyclopedia of Food and Health. Academic Press. 2016. 331-338. 9780123849533. DOI: 10.1016/B978-0-12-384947-2.00699-1

Sornwichate Rattanachaiwong, Pierre Singer. Diets and Diet Therapy: Trace Elements. Pasquale Ferranti, Elliot M. Berry, Jock R. Anderson. Encyclopedia of Food Security and Sustainability. Elsevier. 2019. 143-160. 9780128126882. DOI: 10.1016/B978-0-08-100596-5.21941-0

Steven M. Lonergan, David G. Topel, Dennis N. Marple. Chapter 13 - Fresh and cured meat processing and preservation. Steven M. Lonergan, David G. Topel, Dennis N. Marple. The Science of Animal Growth and Meat Technology (Second Edition). Academic Press. 2019. 205-228. 9780128152775. DOI: 10.1016/B978-0-12-815277-5.00013-5

Martin Kohlmeier. Chapter 11 - Minerals and Trace Elements. Martin Kohlmeier. Nutrient Metabolism (Second Edition). Academic Press. 2015. 673-807. 9780123877840. DOI: 10.1016/B978-0-12-387784-0.00011-0

H.W. Ockerman, L. Basu. BY-PRODUCTS | Edible, for Human Consumption. Michael Dikeman, Carrick Devine. Encyclopedia of Meat Sciences (Second Edition). Academic Press. 2014. 104-111. 9780123847348. DOI: 10.1016/B978-0-12-384731-7.00031-3

Robert Heaney. Chapter 42 – Osteoporosis. Ann M. Coulston, Cheryl L. Rock, Elaine R. Monsen. Nutrition in the Prevention and Treatment of Disease. Academic Press. 2001. 653-684. 9780121931551. DOI: 10.1016/B978-012193155-1/50044-1

R.A. Lawrie. Chapter 5 - The conversion of muscle to meat. R.A. Lawrie. In Woodhead Publishing Series in Food Science. Technology and Nutrition. Lawrie's Meat Science (Seventh Edition). Woodhead Publishing. 2006. 128-156. 9781845691592. DOI: 10.1533/9781845691615.128

Martin Kohlmeier. Chapter 8 - Amino Acids and Nitrogen Compounds. Martin Kohlmeier. Nutrient Metabolism (Second Edition). Academic Press. 2015. 265-477. 9780123877840. DOI: 10.1016/B978-0-12-387784-0.00008-

Bashey, R. I., Bashey, H. M., & Jimenez, S. A. (1978). Characterization of pepsin-solubilized bovine heart-valve collagen. The Biochemical journal, 173(3), 885–894. DOI: 10.1042/bj1730885

Jimenez, S. A., & Bashey, R. I. (1978). Solubilization of bovine heart-value collagen. The Biochemical journal, 173(1), 337–340. DOI: 10.1042/bj1730337

Cole, W. G., Chan, D., Hickey, A. J., & Wilcken, D. E. (1984). Collagen composition of normal and myxomatous human mitral heart valves. The Biochemical journal, 219(2), 451–460. DOI: 10.1042/bj2190451

Beef Liver

Duizer, L. M., Diana, A., Rathomi, H. S., Luftimas, D. E., Rahmannia, S., Santi, W., Nugraha, G. I., Haszard, J. J., Gibson, R. S., & Houghton, L. A. (2017). An Acceptability Trial of Desiccated Beef Liver and Meat Powder as Potential Fortifiers of Complementary Diets of Young Children in Indonesia. Journal of food science, 82(9), 2206–2212. DOI: 10.1111/1750-3841.13807

Ross, A. C., Caballero, B. H., Cousins, R. J., Tucker, K. L., & Ziegler, T. R. (2012). Modern nutrition in health and disease: Eleventh edition. Wolters Kluwer Health Adis (ESP).

Sanders LM, Zeisel SH. Choline: Dietary Requirements and Role in Brain Development. Nutr Today. 2007;42(4):181-186. doi: 10.1097/01.NT.0000286155.55343.fa

Zeisel SH, da Costa KA. Choline: an essential nutrient for public health. Nutr Rev. 2009;67(11):615-623. doi: 10.1111/j.1753-4887.2009.00246.x

Ercan Karaayak, Pınar & El, Sedef. (2011). Changes in content of coenzyme Q10 in beef muscle, beef liver and beef heart with cooking and in vitro digestion. Journal of Food Composition and Analysis - J FOOD COMPOS ANAL. 24. DOI: 10.1016/j.jfca.2011.05.002

Prakash S, Sunitha J, Hans M. Role of coenzyme Q(10) as an antioxidant and bioenergizer in periodontal diseases. Indian J Pharmacol. 2010;42(6):334-337. doi: 10.4103/0253-7613.71884

Rosenfeldt, Franklin & Hilton, Deborah & Pepe, Salvatore & Krum, Henry. (2003). Systematic review of effect of coenzyme Q10 in physical exercise, hypertension and heart failure. BioFactors (Oxford, England). 18. 91-100. DOI: 10.1002/biof.5520180211.

Jafari, M., Mousavi, S. M., Asgharzadeh, A., & Yazdani, N. (2018). Coenzyme Q10 in the treatment of heart failure: A systematic review of systematic reviews. Indian heart journal, 70 Suppl 1(Suppl 1), S111–S117. DOI: 10.1016/j.ihj.2018.01.031

Ueland P. M. (2011). Choline and betaine in health and disease. Journal of inherited metabolic disease, 34(1), 3–15. DOI: 10.1007/s10545-010-9088-4

Vitamin B2

Suwannasom N, Kao I, Pruß A, Georgieva R, Bäumler H. Riboflavin: The Health Benefits of a Forgotten Natural Vitamin. Int J Mol Sci. 2020;21(3):950. Published 2020 Jan 31. doi: 10.3390/ijms21030950

Saedisomeolia, A., & Ashoori, M. (2018). Riboflavin in Human Health: A Review of Current Evidences. Advances in food and nutrition research, 83, 57–81. DOI: 10.1016/bs.afnr.2017.11.002

Ashoori, M., & Saedisomeolia, A. (2014). Riboflavin (vitamin B₂) and oxidative stress: a review. The British journal of nutrition, 111(11), 1985–1991. DOI: 10.1017/S0007114514000178

Namazi, N., Heshmati, J., & Tarighat-Esfanjani, A. (2015). Supplementation with Riboflavin (Vitamin B2) for Migraine Prophylaxis in Adults and Children: A Review. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 85(1-2), 79–87. DOI: 10.1024/0300-9831/a000225

Rokitzki, L., Sagredos, A., Keck, E., Sauer, B., & Keul, J. (1994). Assessment of vitamin B2 status in performance athletes of various types of sports. Journal of nutritional science and vitaminology, 40(1), 11–22. DOI: 10.3177/jnsv.40.11

Vitamin B6

Spinneker, A., Sola, R., Lemmen, V., Castillo, M. J., Pietrzik, K., & González-Gross, M. (2007). Vitamin B6 status, deficiency and its consequences--an overview. Nutricion hospitalaria, 22(1), 7–24. PMID: 17260529

Bird R. P. (2018). The Emerging Role of Vitamin B6 in Inflammation and Carcinogenesis. Advances in food and nutrition research, 83, 151–194. DOI: 10.1016/bs.afnr.2017.11.004

Rosenberg, J., Ischebeck, T., & Commichau, F. M. (2017). Vitamin B6 metabolism in microbes and approaches for fermentative production. Biotechnology advances, 35(1), 31–40. DOI: 10.1016/j.biotechadv.2016.11.004

Ramos, R. J., Pras-Raves, M. L., Gerrits, J., van der Ham, M., Willemsen, M., Prinsen, H., Burgering, B., Jans, J. J., & Verhoeven-Duif, N. M. (2017). Vitamin B6 is essential for serine de novo biosynthesis. Journal of inherited metabolic disease, 40(6), 883–891. DOI: 10.1007/s10545-017-0061-3

Friso, S., Lotto, V., Corrocher, R., & Choi, S. W. (2012). Vitamin B6 and cardiovascular disease. Sub-cellular biochemistry, 56, 265–290. DOI: 10.1007/978-94-007-2199-9_14

Iqbal, M. P., Ishaq, M., Kazmi, K. A., Yousuf, F. A., Mehboobali, N., Ali, S. A., Khan, A. H., & Waqar, M. A. (2005). Role of vitamins B6, B12 and folic acid on hyperhomocysteinemia in a Pakistani population of patients with acute myocardial infarction. Nutrition, metabolism, and cardiovascular diseases : NMCD, 15(2), 100–108. DOI: 10.1016/j.numecd.2004.05.003

Herrmann, W., Lorenzl, S., & Obeid, R. (2007). Hyperhomocysteinämie und B-Vitaminmangel bei neurologischen und psychiatrischen Erkrankungen--Aktueller Kenntnisstand und vorläufige Empfehlungen [Review of the role of hyperhomocysteinemia and B-vitamin deficiency in neurological and psychiatric disorders--current evidence and preliminary recommendations]. Fortschritte der Neurologie-Psychiatrie, 75(9), 515–527. DOI: 10.1055/s-2007-980112

Vitamin B12

Lin, C. Y., Kuo, C. S., Lu, C. L., Wu, M. Y., & Huang, R. F. (2010). Elevated serum vitamin B(12) levels in association with tumor markers as the prognostic factors predictive for poor survival in patients with hepatocellular carcinoma. Nutrition and cancer, 62(2), 190–197. DOI: 10.1080/01635580903305334

Majaj A. S. (1966). Vitamin E-responsive macrocytic anemia in protein-calorie malnutrition. Measurements of vitamin E, folic acid, vitamin C, vitamin B12 and iron. The American journal of clinical nutrition, 18(5), 362–368. DOI: 10.1093/ajcn/18.5.362

Kwok, T., Tang, C., Woo, J., Lai, W. K., Law, L. K., & Pang, C. P. (1998). Randomized trial of the effect of supplementation on the cognitive function of older people with subnormal cobalamin levels. International journal of geriatric psychiatry, 13(9), 611–616. DOI: 10.1002/(sici)1099-1166(199809)13:9<611::aid-gps832>3.0.co;2-o

Lonn, E., Yusuf, S., Arnold, M. J., Sheridan, P., Pogue, J., Micks, M., McQueen, M. J., Probstfield, J., Fodor, G., Held, C., Genest, J., Jr, & Heart Outcomes Prevention Evaluation (HOPE) 2 Investigators (2006). Homocysteine lowering with folic acid and B vitamins in vascular disease. The New England journal of medicine, 354(15), 1567–1577. DOI: 10.1056/NEJMoa060900

Kwok, T., Lee, J., Law, C. B., Pan, P. C., Yung, C. Y., Choi, K. C., & Lam, L. C. (2011). A randomized placebo controlled trial of homocysteine lowering to reduce cognitive decline in older demented people. Clinical nutrition (Edinburgh, Scotland), 30(3), 297–302. DOI: 10.1016/j.clnu.2010.12.004

Clarke R. (2000). Lowering blood homocysteine with folic acid-based supplements: meta-analysis of randomised trials. Indian heart journal, 52(7 Suppl), S59–S64. PMID: 11339443

Ma, E., Iwasaki, M., Kobayashi, M., Kasuga, Y., Yokoyama, S., Onuma, H., Nishimura, H., Kusama, R., & Tsugane, S. (2009). Dietary intake of folate, vitamin B2, vitamin B6, vitamin B12, genetic polymorphism of related enzymes, and risk of breast cancer: a case-control study in Japan. Nutrition and cancer, 61(4), 447–456. DOI: 10.1080/01635580802610123

Malouf, R., & Areosa Sastre, A. (2003). Vitamin B12 for cognition. The Cochrane database of systematic reviews, (3), CD004326. DOI: 10.1002/14651858.CD004326

Malouf, R., & Grimley Evans, J. (2008). Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people. The Cochrane database of systematic reviews, (4), CD004514. DOI: 10.1002/14651858.CD004514.pub2

McNulty, H., Pentieva, K., Hoey, L., & Ward, M. (2008). Homocysteine, B-vitamins and CVD. The Proceedings of the Nutrition Society, 67(2), 232–237. DOI: 10.1017/S0029665108007076

Chen, K. J., Pan, W. H., Yang, F. L., Wei, I. L., Shaw, N. S., & Lin, B. F. (2005). Association of B vitamins status and homocysteine levels in elderly Taiwanese. Asia Pacific journal of clinical nutrition, 14(3), 250–255. PMID: 16169836