Zinc (como citrato), mezcla de integridad intestinal: L-glutamina, regaliz desglicirricinado (raíz), malvavisco (raíz), hongo tónico, microalgas y mezcla de minerales: espirulina, maitake (Grifola frondosa; cuerpos fructíferos), polvo de hongo cola de pavo ( Trametes versicolor, cuerpos fructíferos), mezcla de probióticos y prebióticos a base de plantas y suelos (10 mil millones de UFC†): Saccharomyces boulardii, Bacillus clausii, Bacillus coagulans, Bacillus subtilis, Myoviridae T4, Myoviridae LH01, Myoviridae LL12. Otros ingredientes: Cápsula de metilcelulosa.

†En el momento de la fabricación.

Los adultos toman 3 cápsulas al día con 8 onzas de agua o su bebida favorita. Puede tomarse con o sin alimentos.

PRECAUCIÓN: No exceda la dosis recomendada. Las mujeres embarazadas, las madres lactantes, los niños menores de 18 años y las personas con una afección médica conocida deben consultar a un médico antes de usar este o cualquier suplemento dietético. Tenga cuidado si tiene alergias o sensibilidades a alguno de los ingredientes enumerados. Mantener fuera del alcance de los niños y las mascotas. No lo utilice si el sello de seguridad está dañado o falta. Guardar en un lugar fresco y seco. Utilice este producto únicamente como complemento alimenticio. No utilice para la reducción de peso.

Soil & Plant Based Prebiotic

Davani-Davari D, Negahdaripour M, Karimzadeh I, et al. Prebiotics: Definition, Types, Sources, Mechanisms, and Clinical Applications. Foods. 2019;8(3):92. Published 2019 Mar 9. doi:10.3390/foods8030092

Justin L Carlson, Jennifer M Erickson, Beate B Lloyd, Joanne L Slavin, Health Effects and Sources of Prebiotic Dietary Fiber, Current Developments in Nutrition, Volume 2, Issue 3, March 2018, nzy005, https://doi.org/10.1093/cdn/nzy005

Glenn R. Gibson, Marcel B. Roberfroid, Dietary Modulation of the Human Colonic Microbiota: Introducing the Concept of Prebiotics, The Journal of Nutrition, Volume 125, Issue 6, June 1995, Pages 1401–1412, https://doi.org/10.1093/jn/125.6.1401

McBurney MI, Davis C, Fraser CM, et al. Establishing What Constitutes a Healthy Human Gut Microbiome: State of the Science, Regulatory Considerations, and Future Directions. J Nutr. 2019;149(11):1882‐1895. doi:10.1093/jn/nxz154

Yadav, S., Jha, R. Strategies to modulate the intestinal microbiota and their effects on nutrient utilization, performance, and health of poultry. J Animal Sci Biotechnol 10, 2 (2019). https://doi.org/10.1186/s40104-018-0310-9

Greta Jakobsdottir, Margareta Nyman, Frida Fåk,Designing future prebiotic fiber to target metabolic syndrome, Nutrition, Volume 30, Issue 5, 2014, Pages 497-502, ISSN 0899-9007, https://doi.org/10.1016/j.nut.2013.08.013.

La Fata G, Rastall RA, Lacroix C, et al. Recent Development of Prebiotic Research-Statement from an Expert Workshop. Nutrients. 2017;9(12):1376. Published 2017 Dec 20. doi:10.3390/nu9121376

Soil & Plant Based Probiotic

Foster, K., Schluter, J., Coyte, K. et al. The evolution of the host microbiome as an ecosystem on a leash. Nature 548, 43–51 (2017). https://doi.org/10.1038/nature23292

Cuentas, Ana & Deaton, John & Khan, Sonaina & Davidson, John & St Clair, Courtney. (2017). The Effect of Bacillus subtilis DE111 on the Daily Bowel Movement Profile for People with Occasional Gastrointestinal Irregularity. Journal of Probiotics & Health. 05. DOI: 10.4172/2329-8901.1000189

Elshaghabee Fouad M. F., Rokana Namita, Gulhane Rohini D., Sharma Chetan, Panwar Harsh, Bacillus As Potential Probiotics: Status, Concerns, and Future Perspectives, Frontiers in Microbiology. 2017; 8: 1490. DOI=10.3389/fmicb.2017.01490

Casula G, Cutting SM. Bacillus probiotics: spore germination in the gastrointestinal tract. Appl Environ Microbiol. 2002;68(5):2344‐2352. doi: 10.1128/AEM.68.5.2344-2352.2002

Bittner AC, Croffut RM, Stranahan MC, Yokelson TN. Prescript-assist probiotic-prebiotic treatment for irritable bowel syndrome: an open-label, partially controlled, 1-year extension of a previously published controlled clinical trial. Clinical Therapeutics. 2007 Jun;29(6):1153-1160. DOI: 10.1016/j.clinthera.2007.06.010

Hun L. Bacillus coagulans significantly improved abdominal pain and bloating in patients with IBS. Postgraduate Medicine. 2009 Mar;121(2):119-124. DOI: 10.3810/pgm.2009.03.1984

Tonic Mushroom

Hobbs, Christopher. (2004). Medicinal Value of Turkey Tail Fungus Trametes versicolor (L.:Fr.) Pilat (Aphyllophoromycetideae). A Literature Review. International Journal of Medicinal Mushrooms - INT J MED MUSHROOMS. 6. 195-218. DOI: 10.1615/IntJMedMushr.v6.i3.10

Gaoxing Ma, Wenjian Yang, Liyan Zhao, Fei Pei, Donglu Fang, Qiuhui Hu, A critical review on the health promoting effects of mushrooms nutraceuticals, Food Science and Human Wellness. 7, 2, 2018, 125-133, ISSN 2213-453. https://doi.org/10.1016/j.fshw.2018.05.002

Kumar Pallav, Scot E Dowd, Javier Villafuerte, Xiaotong Yang, Toufic Kabbani, Joshua Hansen, Melinda Dennis, Daniel A Leffler, David S Newburg & Ciarán P Kelly (2014) Effects of polysaccharopeptide from Trametes Versicolor on the gut microbiome of healthy volunteers, Gut Microbes, 5:4, 458-467, DOI: 10.4161/gmic.29558

Aritson Cruz, Lígia Pimentel, Luis M. Rodríguez-Alcalá, Tito Fernandes and Manuela Pintado. Health Benefits of Edible Mushrooms Focused on Coriolus versicolor: A Review. Journal of Food and Nutrition Research. 2016; 4(12):773-781. doi: 10.12691/JFNR-4-12-2

Mayell, Mark. “Maitake Extracts and Their Therapeutic Potential - A Review.” (2001).

L-Glutamine

Cruzat V, Macedo Rogero M, Noel Keane K, Curi R, Newsholme P. Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation. Nutrients. 2018;10(11):1564. Published 2018 Oct 23. doi: 10.3390/nu10111564

Michael Gleeson, Dosing and Efficacy of Glutamine Supplementation in Human Exercise and Sport Training, The Journal of Nutrition, Volume 138, Issue 10, October 2008, Pages 2045S–2049S, DOI: 10.1093/jn/138.10.2045S

Rao R, Samak G. Role of Glutamine in Protection of Intestinal Epithelial Tight Junctions. J Epithel Biol Pharmacol. 2012;5(Suppl 1-M7):47‐54. doi: 10.2174/1875044301205010047

Shah, A.M.; Wang, Z.; Ma, J. Glutamine Metabolism and Its Role in Immunity, a Comprehensive Review. Animals 2020, 10, 326. DOI: 10.3390/ani10020326

Kim H. Glutamine as an immunonutrient. Yonsei Med J. 2011;52(6):892‐897. doi: 10.3349/ymj.2011.52.6.892

Calder, P.C., Yaqoob, P. Glutamine and the immune system. Amino Acids 17, 227–241 (1999). https://doi.org/10.1007/BF01366922

Wang, B., Wu, G., Zhou, Z. et al. Glutamine and intestinal barrier function. Amino Acids 47, 2143–2154 (2015). https://doi.org/10.1007/s00726-014-1773-4

Zinc

Maggini S, Pierre A, Calder PC. Immune Function and Micronutrient Requirements Change over the Life Course. Nutrients. 2018;10(10):1531. Published 2018 Oct 17. doi: 10.3390/nu10101531

Gombart AF, Pierre A, Maggini S. A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection. Nutrients. 2020;12(1):236. Published 2020 Jan 16. doi: 10.3390/nu12010236

Prasad AS. Zinc in human health: effect of zinc on immune cells. Mol Med. 2008;14(5-6):353‐357. doi: 10.2119/2008-00033.Prasad

Melissa L. Zastrow and Vincent L. Pecoraro. Designing Hydrolytic Zinc Metalloenzymes. Biochemistry 2014 53 (6), 957-978. February 7, 2014. DOI: 10.1021/bi4016617

Technical University of Munich (TUM). "Diet lacking in zinc is detrimental to human, animal health: Even moderate zinc deficiency is bad for digestion." ScienceDaily. ScienceDaily, 9 June 2016.