Magnesium l-threonate, or MgT, is one of the newest forms of magnesium supplementation available. With potential benefits ranging from supporting cognitive function to potentially playing a role on some aspects of mental health, it has become a subject of increasing interest within the world of health, nutrition, and scientific research.* Let's delve into its history, biology, use in supplements, and other interesting facts about this unique compound.
History
The story of magnesium l-threonate begins with the essential mineral, magnesium. Magnesium has been known for centuries as a crucial element required for a myriad of biological functions. The human body requires magnesium for more than 300 biochemical reactions, making it a nutrient for supporting health.
However, the discovery of magnesium l-threonate as a unique compound is much more recent. Magnesium l-threonate was first patented in 2009 by a team of neuroscientists at the Massachusetts Institute of Technology (MIT), including Dr. Guosong Liu, one of the world's leading cognitive health researchers. Their research was focused on identifying substances, including minerals that could promote cognitive function.* You can read about the different types of magnesium.
Biology
The discovery of magnesium l-threonate was rooted in the biology of the brain. To affect cognitive function, a substance must first cross the blood-brain barrier, a protective boundary that separates the brain from the bloodstream. This barrier is believed to be vital for brain health as it may help protect the brain from harmful substances that may be present in the blood.*
While all forms of magnesium have a certain level of bioavailability, not all of them might efficiently cross the blood-brain barrier. The team at MIT discovered that magnesium l-threonate seemed more effective than other forms of magnesium at crossing this barrier, making it a form of magnesium for targeting the brain.*
Magnesium may play a role in supporting brain health and function.* It might help regulate neurotransmitters, which send signals throughout the brain and nervous system. Magnesium might also plays a role in the regulation of NMDA receptors, which are thought to be important for brain development, memory, and learning.* One of the concepts behind magnesium l-threonate is how it could support the concentration of magnesium in the brain and potentially promote these functions.*
Magnesium L-Threonate supplements
In recent years, magnesium l-threonate has made its way to the market as a dietary supplement. Its bioavailability and potential to cross the blood-brain barrier make it an appealing option for those looking to support cognitive function as part of a healthy regimen.*
While more research is needed to confirm and understand the full range of its effects, early studies suggest that magnesium l-threonate may support cognitive abilities such as short-term memory, long-term memory, and learning ability for some individuals and in some environments. However, it should be noted that while promising, these results are preliminary, and more research is always required.
Other interesting facts
In addition to its potential cognitive benefits, magnesium l-threonate may also have a positive impact on other health functions. Some research has suggested that it could play a role with on some aspects of mental health and sleep. Other studies have highlighted its potential benefits for cardiovascular health.*
Also interesting to note is that the "L-threonate" part of magnesium l-threonate is derived from L-threonic acid, a metabolite of vitamin C. This does not mean that magnesium l-threonate provides vitamin C, but it's a fascinating connection between these two important nutrients.
While the world of nutrition and health supplements is vast and complex, magnesium l-threonate stands out as a unique and intriguing compound. With its potential support for cognitive health and overall well-being, it represents an exciting frontier in our understanding of how specific nutrients can support brain function.*
However, it is crucial to remember that while supplements can support our health, they are not a replacement for a balanced diet, regular exercise, and adequate sleep. Always consult with a healthcare professional before starting any new supplement regimen. As we continue to explore the potential of magnesium l-threonate, there is much hope for the ways it could promote human health in the future.